What is peripheral neuropathy commonly associated with?

Peripheral neuropathy is primarily associated with damage to the nerves, particularly in the lower legs and hands, often resulting from prolonged high blood sugar levels in individuals with diabetes mellitus. Over time, diabetes can lead to nerve damage as a consequence of various biochemical processes, including the accumulation of damaging substances and reduced blood flow to peripheral nerves. This damage can manifest as pain, tingling, numbness, or weakness in the affected areas, which are hallmark symptoms of peripheral neuropathy.

While other conditions, like cardiovascular disease or increased risk of infection, may be related to general health issues associated with diabetes, they do not specifically define what peripheral neuropathy is or its primary cause. Joint pain and stiffness are typically linked to musculoskeletal issues or inflammatory conditions rather than nerve damage. Understanding the root of peripheral neuropathy in the context of diabetes highlights the importance of blood sugar control to prevent the progression of nerve damage.